{"id":41229,"date":"2026-09-23T10:27:43","date_gmt":"2026-09-23T04:57:43","guid":{"rendered":"https:\/\/mdforlives.com\/blog\/?p=41229"},"modified":"2026-09-23T10:30:08","modified_gmt":"2026-09-23T05:00:08","slug":"sustained-retinal-drug-delivery","status":"publish","type":"post","link":"https:\/\/mdforlives.com\/blog\/sustained-retinal-drug-delivery\/","title":{"rendered":"Beyond Repeated Injections: What Would Make Sustained Retinal Drug Delivery Worth the Shift?\u00a0"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"41229\" class=\"elementor elementor-41229\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5ff00724 e-con-full e-flex e-con e-parent\" data-id=\"5ff00724\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-403a84c8 elementor-widget elementor-widget-text-editor\" data-id=\"403a84c8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"post-heading\"><div class=\"categ\"><p><span data-contrast=\"auto\">Repeated intravitreal injections work. That is not the debate.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The harder question is what happens when treatment works, but the routine around it becomes difficult to sustain.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">For many retina practices, anti-VEGF therapy has changed outcomes across retinal disease. But it has also created a long-term care model built around repeated visits, scheduling pressure, patient persistence, procedural tolerance, and clinic capacity. The burden is not only clinical. It is operational, behavioral, and logistical.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">That is why sustained retinal drug delivery is becoming a more practical conversation. The question is no longer whether repeated injection burden exists. The question is what kind of alternative would feel clinically worth adopting.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">MDForLives survey data shows a clear tension: ophthalmologists recognize the burden of repeated intravitreal therapy, but remain cautious about implantable sustained-delivery platforms unless safety, durability, logistics, and patient selection become clearer.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">Repeated Injection Burden Is Real, but Not Uniform<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">The burden signal is strong. In the survey data, 21.6% described repeated intravitreal injection burden as extremely high, affecting both adherence and clinic workflow. Another 32.4% described it as high, with visible strain on persistence and scheduling.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Together, that means more than half of responding ophthalmologists see injection burden as a major pressure point.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">But the data also shows nuance. Nearly 29.7% called the burden moderate, manageable but suboptimal. This suggests that sustained retinal drug delivery is not being viewed as a universal replacement. It is being considered where the current injection model starts to strain continuity, persistence, or capacity.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">The Biggest Limitation Is Not the Injection Alone<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">When asked about the single greatest limitation of repeated intravitreal therapy, 35.1% selected visit and scheduling burden. Clinic capacity constraints and procedural burden or patient tolerance followed at 21.6% each.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">This matters because the problem is broader than the procedure itself.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">A patient may tolerate injections medically, but still struggle with transportation, caregiver support, time off work, anxiety, follow-up frequency, or cumulative fatigue. A clinic may deliver injections efficiently, but still face capacity limits when chronic retinal disease requires long-term, repeated treatment.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The data points to a practical insight: burden accumulates around the injection, not only inside it.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">That is where sustained retinal drug delivery becomes relevant. Its value would not be judged only by drug durability. It would be judged by whether it reduces the care-system load without introducing equal or greater complexity elsewhere.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">Which Patients Make the Case Strongest?<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">Ophthalmologists are not thinking about sustained delivery as a broad first-line shift. They are identifying specific patient profiles.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">In the survey data, 34.3% said patients with high injection frequency over time most strongly make them consider a sustained-delivery alternative. Another 22.9% pointed to patients losing persistence with follow-up, while 20.0% selected patients in whom visit burden threatens continuity.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">This creates a clear adoption logic.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The case for sustained retinal drug delivery becomes strongest when repeated treatment is not only frequent, but fragile. If ongoing injection frequency threatens adherence, continuity, or clinic feasibility, an alternative delivery model becomes more clinically meaningful.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">That is different from adopting innovation because it is new. It is adopting it because the existing care model is beginning to fail a specific patient need.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">Familiarity Is Growing, but Confidence Is Conditional<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">The survey data shows that 17.1% are very familiar with sustained-delivery retinal platforms and following them closely. Another 45.7% are familiar with the main data and practical issues.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">This indicates that awareness is no longer low.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Still, confidence remains measured. About 37.1% said implantable sustained-delivery systems could meaningfully change practice in selected patients. Another 28.6% said they are promising, but still need stronger real-world confidence. Smaller groups expect them to remain niche or say their practical value is still uncertain.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">That is a balanced adoption posture.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Ophthalmologists are not dismissing sustained retinal drug delivery. But they are also not treating it as a simple burden-reduction solution. For many, the promise is credible only if real-world safety, durability, and workflow value hold up beyond selected scenarios.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">Surgical Risk Is the Main Adoption Barrier<\/span><\/b><\/h2><p><span data-ccp-props=\"{}\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-41333\" src=\"https:\/\/mdforlives.com\/blog\/wp-content\/uploads\/2026\/09\/Ophthalmology_Beyond-Repeated-Injections_Inner1.png\" alt=\"retinal drug delivery infographic showing injection burden visit scheduling burden and surgical risk concern\" width=\"800\" height=\"400\" srcset=\"https:\/\/mdforlives.com\/blog\/wp-content\/uploads\/2026\/09\/Ophthalmology_Beyond-Repeated-Injections_Inner1.png 800w, https:\/\/mdforlives.com\/blog\/wp-content\/uploads\/2026\/09\/Ophthalmology_Beyond-Repeated-Injections_Inner1-300x150.png 300w, https:\/\/mdforlives.com\/blog\/wp-content\/uploads\/2026\/09\/Ophthalmology_Beyond-Repeated-Injections_Inner1-768x384.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/span><span data-contrast=\"auto\">The strongest hesitation around implantable delivery is risk. In the survey data, 45.7% selected surgical risk and device-related complications as their greatest concern. Cost and reimbursement barriers followed at 20.0%, while refill, monitoring, and clinic logistics were selected by 17.1%.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">This is the central trade-off.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Repeated injections carry ongoing burden, but they are familiar. Implantable delivery may reduce frequency, but it introduces procedural and device-related considerations that change the risk profile.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">That is why the most important adoption question is not, \u201cCan this reduce visits?\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">It is, \u201cDoes the reduction in visits justify the procedural risk, monitoring model, refill logistics, and long-term uncertainty?\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">When Would Sustained Delivery Feel Justified?<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">The answer is practical and patient-specific. In the survey data, 40.0% said sustained delivery feels most justified when disease control requires long-term frequent treatment. Another 37.1% selected cases where injection burden is clearly affecting persistence.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">This suggests that ophthalmologists want the threshold for adoption to be anchored in real patient burden and long-term treatment need.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The trade-off data reinforces this. Durability versus procedural risk and reduced visit burden versus monitoring complexity were each selected by 34.3% as the most important decision trade-off.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">That is the core of sustained retinal drug delivery today: durability is valuable, but only when the added procedural and monitoring demands are acceptable.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">Topical Therapies Are Interesting, but Not Replacements Yet<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">The survey also explored topical retinal therapies as a future burden-reduction strategy. The leading view, at 37.1%, was that topical approaches are more likely to serve as an adjunct than a replacement. Another 25.7% saw them as potentially meaningful in selected settings, while 20.0% called them scientifically interesting but clinically uncertain.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">This reinforces the same theme.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Ophthalmologists are open to less burdensome delivery. But the retina is a high-efficacy environment where promise must translate into sufficient drug exposure, durable effect, and meaningful outcomes. Convenience alone is not enough.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">What Would Move the Field Forward?<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">The strongest answer is evidence. Nearly 48.6% said stronger long-term safety and durability data would most increase willingness to adopt advanced retinal drug delivery systems. Another 25.7% wanted stronger real-world evidence of adherence or outcome benefit.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">This is the clearest message in the MDForLives survey data.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The path forward for sustained retinal drug delivery is not just better technology. It is better confidence.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Ophthalmologists need to see whether these systems can reduce burden without compromising safety, whether patients remain persistent, whether refill and monitoring logistics work in routine practice, and whether outcomes remain comparable or better over time.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><h2><b><span data-contrast=\"auto\">Closing Perspective<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/h2><p><span data-contrast=\"auto\">Repeated intravitreal injections remain effective, but effectiveness does not erase burden.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The MDForLives survey data shows that ophthalmologists are actively weighing the next phase of retinal drug delivery. Sustained delivery is not being rejected. It is being evaluated through a practical clinical lens: which patients benefit, what risks are acceptable, how durable the effect is, and whether the model truly reduces burden rather than shifting it.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The future of sustained retinal drug delivery will depend less on novelty and more on fit.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">For retina specialists, the question is not simply whether treatment can last longer.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">It is whether longer-lasting treatment can be delivered safely, sustainably, and with enough real-world confidence to change routine care.<\/span><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b431c31 elementor-widget elementor-widget-heading\" data-id=\"b431c31\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Frequently Asked Questions<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-25d4a7b elementor-widget elementor-widget-n-accordion\" data-id=\"25d4a7b\" data-element_type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;expanded&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3960\" class=\"e-n-accordion-item\" open>\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"true\" aria-controls=\"e-n-accordion-item-3960\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> What is sustained retinal drug delivery? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"fas fa-angle-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"fas fa-angle-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3960\" class=\"elementor-element elementor-element-5441838 e-con-full e-flex e-con e-child\" data-id=\"5441838\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6ee2459 elementor-widget elementor-widget-text-editor\" data-id=\"6ee2459\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW235966463 BCX8\" lang=\"EN-IN\" xml:lang=\"EN-IN\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW235966463 BCX8\">Sustained retinal drug delivery refers to treatment approaches designed to release medication into the eye over a longer period, potentially reducing the need for frequent intravitreal injections.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3961\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3961\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Why are repeated intravitreal injections burdensome? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"fas fa-angle-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"fas fa-angle-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3961\" class=\"elementor-element elementor-element-9ffac9e e-con-full e-flex e-con e-child\" data-id=\"9ffac9e\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d8a68dc elementor-widget elementor-widget-text-editor\" data-id=\"d8a68dc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW45761368 BCX8\" lang=\"EN-IN\" xml:lang=\"EN-IN\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW45761368 BCX8\">They can create visit and scheduling pressure, affect patient persistence, increase clinic capacity demands, and add procedural burden over long-term treatment.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3962\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3962\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Which patients may be most suitable for sustained retinal drug delivery? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"fas fa-angle-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"fas fa-angle-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3962\" class=\"elementor-element elementor-element-95847b8 e-con-full e-flex e-con e-child\" data-id=\"95847b8\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-83a3ce2 elementor-widget elementor-widget-text-editor\" data-id=\"83a3ce2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW222798143 BCX8\" lang=\"EN-IN\" xml:lang=\"EN-IN\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW222798143 BCX8\">Based on MDForLives survey data, ophthalmologists most often consider it for patients with high injection frequency over time, loss of follow-up persistence, or visit burden threatening continuity.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3963\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"4\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3963\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> What is the biggest concern with implantable retinal delivery systems? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"fas fa-angle-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"fas fa-angle-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3963\" class=\"elementor-element elementor-element-f29a337 e-con-full e-flex e-con e-child\" data-id=\"f29a337\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-80c42d3 elementor-widget elementor-widget-text-editor\" data-id=\"80c42d3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW47425174 BCX8\" lang=\"EN-IN\" xml:lang=\"EN-IN\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW47425174 BCX8\">The leading concern in the survey data was surgical risk and device-related complications, followed by reimbursement barriers and refill or monitoring logistics.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3964\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"5\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3964\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Are topical retinal therapies likely to replace injections? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"fas fa-angle-up\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"fas fa-angle-down\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3964\" class=\"elementor-element elementor-element-4727f24 e-con-full e-flex e-con e-child\" data-id=\"4727f24\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-62a1fc3 elementor-widget elementor-widget-text-editor\" data-id=\"62a1fc3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW97576366 BCX8\" lang=\"EN-IN\" xml:lang=\"EN-IN\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW97576366 BCX8\">Most surveyed ophthalmologists viewed topical retinal therapies as more likely to serve as adjuncts than replacements, with retinal efficacy and clinical durability still uncertain.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3965\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"6\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3965\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> What would increase adoption of sustained retinal drug delivery? 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