Studies Shed New Light on Estrogen Receptor-Positive Breast Cancer
Nearly 80% of breast cancer are estrogen receptor-positive and endocrine therapy resistance occurs in approximately 30% of them.1 Researchers...
Potential New Targets to Treat Acute Myeloid Leukemia
Researchers have discovered new therapeutic targets for acute myeloid leukemia (AML). A new study published in Stem Cells suggests...
A checkpoint inhibitor gains FDA approval in endometrial cancer
On April 22, 2021, the US Food and Drug Administration (FDA) granted Accelerated Approval to dostarlimab (Jemperli, GlaxoSmithKline) as...
Recent developments in primary hyperoxaluria treatment
Primary hyperoxaluria (PH) is a rare genetic disease in which high levels of oxalate are produced and can deposit...
FDA Approves First Trial of CRISPR for Sickle Cell Disease
The U.S Food and Drug Administration (FDA) has approved the first clinical trial of CRISPR to correct sickle cell...
Circadian Clock Protein CRY1 – The Novel Target for Prostate Cancer
Prostate cancer is one of the most common cancers and a second leading cause of cancer death in American...
CAR-T Therapy Approved for B-Cell Non-Hodgkin Lymphoma
Non-Hodgkin lymphoma treatment traditionally relied on chemotherapy, radiation, and bone marrow transplant. More recently, immuno-oncology treatments have come to...
Bispecific antibodies are progressing in cancer clinical trials
The human immune system makes antibodies that bind to the same antigen with both of their variable regions, or...
CRISPR-Based Diagnostics on the Rise
In 2020, the Nobel Prize in Chemistry was awarded for “the development of a method for genome editing” based...
Can the Stages of Chronic Kidney Disease (CKD) be Reversed?
Chronic kidney disease (CKD), a global public issue is associated with substantial morbidity and mortality. In the past few...