Positive Phase 3 trial results for an atopic dermatitis therapy
Atopic dermatitis, often called eczema, affects people of all ages. It is a chronic inflammatory skin condition 1 that...
Panelist Diaries: What makes a good endpoint in cancer management?
In Plato’s book, The Theaetetus, Socrates was at wrestling school, discussing what he believed ‘knowledge’ to be to his...
A checkpoint inhibitor gains FDA approval in endometrial cancer
On April 22, 2021, the US Food and Drug Administration (FDA) granted Accelerated Approval to dostarlimab (Jemperli, GlaxoSmithKline) as...
Recent developments in primary hyperoxaluria treatment
Primary hyperoxaluria (PH) is a rare genetic disease in which high levels of oxalate are produced and can deposit...
Cancer vaccines in the clinic and in trials
Most vaccines are given as prophylactics, agents that protect healthy individuals before exposure to a pathogen. By contrast, therapeutic...
FDA Approves First Trial of CRISPR for Sickle Cell Disease
The U.S Food and Drug Administration (FDA) has approved the first clinical trial of CRISPR to correct sickle cell...
Exon-skipping drug approved for the third subtype of Duchenne muscular dystrophy
Discovering treatments for Duchenne muscular dystrophy has been difficult because the disease is a result of a wide variety...
CAR-T Therapy Approved for B-Cell Non-Hodgkin Lymphoma
Non-Hodgkin lymphoma treatment traditionally relied on chemotherapy, radiation, and bone marrow transplant. More recently, immuno-oncology treatments have come to...
A new device for mild sleep apnea
Most non-surgical options for managing mild sleep apnea simply keep the airway open while the individual sleeps. A new...
CRISPR-Based Diagnostics on the Rise
In 2020, the Nobel Prize in Chemistry was awarded for “the development of a method for genome editing” based...