Panelist Diaries: What makes a good endpoint in cancer management?
In Plato’s book, The Theaetetus, Socrates was at wrestling school, discussing what he believed ‘knowledge’ to be to his...
Cancer vaccines in the clinic and in trials
Most vaccines are given as prophylactics, agents that protect healthy individuals before exposure to a pathogen. By contrast, therapeutic...
Lung Cancer – Navigating through the maze
When it comes to lung cancer, the patient and the physician often feel like Danny in The Shining, navigating...
FDA Approves Pembrolizumab, the First Anti-PD1 Therapy for HER2 Positive Gastric Cancer
The Food and Drug Administration grants accelerated approval to Merck’s Keytruda (pembrolizumab), the checkpoint inhibitor drug for HER2-positive gastric...
First-in-class drug approved for bone marrow protection during chemotherapy
Chemotherapy can be lifesaving, but it can also damage bone marrow and cause blood cell counts to drop, sometimes...
Circadian Clock Protein CRY1 – The Novel Target for Prostate Cancer
Prostate cancer is one of the most common cancers and a second leading cause of cancer death in American...
CAR-T Therapy Approved for B-Cell Non-Hodgkin Lymphoma
Non-Hodgkin lymphoma treatment traditionally relied on chemotherapy, radiation, and bone marrow transplant. More recently, immuno-oncology treatments have come to...
Bispecific antibodies are progressing in cancer clinical trials
The human immune system makes antibodies that bind to the same antigen with both of their variable regions, or...
CRISPR-Based Diagnostics on the Rise
In 2020, the Nobel Prize in Chemistry was awarded for “the development of a method for genome editing” based...
The Human Microbiome and the cancer
The interaction of the human microbiome and cancer has been of great interest recently. Two articles published in February...