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New paradigms in Colorectal Cancer – Part 2

New paradigms in Colorectal Cancer – Part 2

Removal of the primary tumor with adequate margins of lymphatic drainage is the key to surgical resection. You can see a breakdown of standard colectomies for adenocarcinoma of the colon:

Targeted and Immunotherapies:
Radiation Therapy:

RT is not used in the adjuvant setting in colorectal cancer, though it is an option in palliative settings for brain or bone metastases. Stereotactic RT (e.g., CyberKnife) is an option being studied, while a study by Hendlisz et al. showed that radioembolization with yttrium-90 improved time to liver progression, for unresectable chemo-refractory patients.

Other measures:

Improvements in the following criteria are also important based on numerous studies.

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