NTRK fusion tumors in adult and pediatric patients
Neurotrophic Tyrosine Kinase genes (NTRK1, NTRK2 and NTRK3) encode members of the tyrosine receptor kinase (TRK) protein family: TRKA,...
NSCLC
Management of rare mutations in non-small cell lung cancer (NSCLC) – PART 3: HER2
Human epidermal growth factor receptor 2 (HER2) is a member of the ERBB receptor tyrosine kinase family. It is...
Management of rare mutations in non-small cell lung cancer (NSCLC) – PART 2: RET, NTRK1
RET RET (an abbreviation for Rearranged during Transfection) encodes a receptor tyrosine kinase for members of the glial cell...
Management of rare mutations in non-small cell lung cancer (NSCLC) – PART 1: MET, ROS1, and ALK
Why do we make a fuss about rare mutations in NSCLC? In 2015, they only made up about 1-2%...
Recent developments in therapy for HER2+ and HER2- Non-small cell lung cancer
Lung cancer kills more people worldwide than breast, prostate, colorectal, and brain cancers combined.1 Non-small cell lung cancer (NSCLC)...